hrp0092t3 | Top 20 Poster | ESPE2019

Hypothalamus and Pituitary Gland Antibodies in Childhood-Onset Brain Tumors and Pituitary Dysfunction

Patti Giuseppa , Calandra Erika , De Bellis Annamaria , Gallizia Annalisa , Napoli Flavia , Crocco Marco , Bellastella Giuseppe , Maiorino Maria Ida , Luisa Garrè Maria , Parodi Stefano , Maghnie Mohamad , Di Iorgi Natascia

Background: Antipituitary (APA) and antihypothalamus antibodies (AHA) have not been investigated in children and adolescents with brain tumors.Patients and Methods: Sixty-three patients with craniopharyngioma, glioma and germinoma treated with surgery and/or chemotherapy and/or radiotherapy were evaluated at a median age of 13 years. Forty-one had MPHD, 6 had a single defect being GH the most common (65.1%), followed...